K25E (p.Lys25Glu) variant of APOA5 (Apolipoprotein A-V)
K25E (p.Lys25Glu) in APOA5 (Apolipoprotein A-V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
K25E (p.Lys25Glu) variant details
- p.Lys25Glu
- Ensembl rs1565325573
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.26
- CADD 22.90
- PolyPhen-2 0.19
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available