W22C (p.Trp22Cys) variant of APOA1 (Apolipoprotein A-I)
W22C (p.Trp22Cys) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
W22C (p.Trp22Cys) variant details
- p.Trp22Cys
- gnomAD 11-116837135-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.661
- REVEL 0.63
- CADD 27.40
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available