V41A (p.Val41Ala) variant of APOA1 (Apolipoprotein A-I)
V41A (p.Val41Ala) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
V41A (p.Val41Ala) variant details
- p.Val41Ala
- gnomAD 11-116837079-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.20
- CADD 22.60
- PolyPhen-2 0.10
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available