S60F (p.Ser60Phe) variant of APOA1 (Apolipoprotein A-I)
S60F (p.Ser60Phe) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
S60F (p.Ser60Phe) variant details
- p.Ser60Phe
- cosmic curated COSV52636
- Missense
- Variant Prioritization Score for Impact Estimate 0.601
- REVEL 0.71
- CADD 23.30
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available