R51T (p.Arg51Thr) variant of APOA1 (Apolipoprotein A-I)
R51T (p.Arg51Thr) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
R51T (p.Arg51Thr) variant details
- p.Arg51Thr
- TOPMed rs1233547311
- gnomAD rs1233547311
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.27
- CADD 17.00
- PolyPhen-2 0.26
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available