Q23L (p.Gln23Leu) variant of APOA1 (Apolipoprotein A-I)
Q23L (p.Gln23Leu) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
Q23L (p.Gln23Leu) variant details
- p.Gln23Leu
- gnomAD 11-116837133-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.62
- CADD 27.70
- PolyPhen-2 0.85
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available