L71P (p.Leu71Pro) variant of APOA1 (Apolipoprotein A-I)
L71P (p.Leu71Pro) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
L71P (p.Leu71Pro) variant details
- p.Leu71Pro
- gnomAD 11-116836400-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- REVEL 0.44
- CADD 23.40
- PolyPhen-2 0.89
- SIFT 0.21
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available