L70F (p.Leu70Phe) variant of APOA1 (Apolipoprotein A-I)
L70F (p.Leu70Phe) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
L70F (p.Leu70Phe) variant details
- p.Leu70Phe
- gnomAD 11-116836404-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.559
- REVEL 0.63
- CADD 24.90
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available