L68Q (p.Leu68Gln) variant of APOA1 (Apolipoprotein A-I)
L68Q (p.Leu68Gln) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, published literature, and structural context.
L68Q (p.Leu68Gln) variant details
- p.Leu68Gln
- gnomAD 11-116836409-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.68
- REVEL 0.76
- CADD 28.90
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available