L38M (p.Leu38Met) variant of APOA1 (Apolipoprotein A-I)
L38M (p.Leu38Met) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
L38M (p.Leu38Met) variant details
- p.Leu38Met
- gnomAD 11-116837089-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.135
- REVEL 0.02
- CADD 7.88
- PolyPhen-2 0.06
- SIFT 0.49
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available