L13R (p.Leu13Arg) variant of APOA1 (Apolipoprotein A-I)
L13R (p.Leu13Arg) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
L13R (p.Leu13Arg) variant details
- p.Leu13Arg
- Ensembl rs1941581716
- Missense
- Variant Prioritization Score for Impact Estimate 0.674
- REVEL 0.69
- CADD 27.00
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available