F57L (p.Phe57Leu) variant of APOA1 (Apolipoprotein A-I)
F57L (p.Phe57Leu) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
F57L (p.Phe57Leu) variant details
- p.Phe57Leu
- gnomAD 11-116837030-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.118
- REVEL 0.12
- CADD 7.30
- PolyPhen-2 0.00
- SIFT 0.44
- Population evidence available
- Structural context available
- Literature evidence available