D37Y (p.Asp37Tyr) variant of APOA1 (Apolipoprotein A-I)
D37Y (p.Asp37Tyr) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
D37Y (p.Asp37Tyr) variant details
- p.Asp37Tyr
- gnomAD 11-116837092-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.687
- REVEL 0.72
- CADD 27.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available
- Literature evidence available