D37N (p.Asp37Asn) variant of APOA1 (Apolipoprotein A-I)
D37N (p.Asp37Asn) in APOA1 (Apolipoprotein A-I) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
D37N (p.Asp37Asn) variant details
- p.Asp37Asn
- TOPMed rs1941570680
- gnomAD rs1941570680
- Missense
- Variant Prioritization Score for Impact Estimate 0.544
- REVEL 0.49
- CADD 26.90
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available