V28M (p.Val28Met) variant of ANGPTL4 (Angiopoietin-related protein 4)
V28M (p.Val28Met) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
V28M (p.Val28Met) variant details
- p.Val28Met
- gnomAD 19-8364403-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.12
- CADD 13.90
- PolyPhen-2 0.27
- SIFT 0.17
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available
- Literature evidence available