V28L (p.Val28Leu) variant of ANGPTL4 (Angiopoietin-related protein 4)
V28L (p.Val28Leu) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
V28L (p.Val28Leu) variant details
- p.Val28Leu
- gnomAD rs1309741165
- Missense
- Variant Prioritization Score for Impact Estimate 0.105
- REVEL 0.03
- CADD 8.84
- PolyPhen-2 0.02
- SIFT 0.62
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available