S22N (p.Ser22Asn) variant of ANGPTL4 (Angiopoietin-related protein 4)
S22N (p.Ser22Asn) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
S22N (p.Ser22Asn) variant details
- p.Ser22Asn
- ExAC rs764188393
- gnomAD rs764188393
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.14
- CADD 22.70
- PolyPhen-2 0.99
- SIFT 0.06
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available