S22G (p.Ser22Gly) variant of ANGPTL4 (Angiopoietin-related protein 4)
S22G (p.Ser22Gly) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
S22G (p.Ser22Gly) variant details
- p.Ser22Gly
- gnomAD rs1396061104
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.14
- CADD 21.80
- PolyPhen-2 0.97
- SIFT 0.07
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available