P27R (p.Pro27Arg) variant of ANGPTL4 (Angiopoietin-related protein 4)
P27R (p.Pro27Arg) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
P27R (p.Pro27Arg) variant details
- p.Pro27Arg
- 1000Genomes rs964963416
- TOPMed rs964963416
- gnomAD rs964963416
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.23
- CADD 21.80
- PolyPhen-2 0.81
- SIFT 0.10
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available