P27L (p.Pro27Leu) variant of ANGPTL4 (Angiopoietin-related protein 4)
P27L (p.Pro27Leu) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
P27L (p.Pro27Leu) variant details
- p.Pro27Leu
- gnomAD 19-8364401-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.21
- CADD 23.10
- PolyPhen-2 0.55
- SIFT 0.01
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available
- Literature evidence available