P27H (p.Pro27His) variant of ANGPTL4 (Angiopoietin-related protein 4)
P27H (p.Pro27His) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
P27H (p.Pro27His) variant details
- p.Pro27His
- gnomAD 19-8364401-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.23
- CADD 23.20
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available
- Literature evidence available