P27A (p.Pro27Ala) variant of ANGPTL4 (Angiopoietin-related protein 4)
P27A (p.Pro27Ala) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
P27A (p.Pro27Ala) variant details
- p.Pro27Ala
- gnomAD 19-8364400-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.12
- CADD 8.42
- PolyPhen-2 0.04
- SIFT 0.34
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available
- Literature evidence available