M12L (p.Met12Leu) variant of ANGPTL4 (Angiopoietin-related protein 4)
M12L (p.Met12Leu) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
M12L (p.Met12Leu) variant details
- p.Met12Leu
- gnomAD 19-8364355-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.1
- REVEL 0.08
- CADD 8.45
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available
- Literature evidence available