L20P (p.Leu20Pro) variant of ANGPTL4 (Angiopoietin-related protein 4)
L20P (p.Leu20Pro) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L20P (p.Leu20Pro) variant details
- p.Leu20Pro
- gnomAD rs1438957737
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.19
- CADD 22.50
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available