G25D (p.Gly25Asp) variant of ANGPTL4 (Angiopoietin-related protein 4)
G25D (p.Gly25Asp) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G25D (p.Gly25Asp) variant details
- p.Gly25Asp
- TOPMed rs1299216887
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.15
- CADD 21.70
- PolyPhen-2 0.86
- SIFT 0.02
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available