C14Y (p.Cys14Tyr) variant of ANGPTL4 (Angiopoietin-related protein 4)
C14Y (p.Cys14Tyr) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
C14Y (p.Cys14Tyr) variant details
- p.Cys14Tyr
- ExAC rs751429634
- TOPMed rs751429634
- gnomAD rs751429634
- Missense
- Variant Prioritization Score for Impact Estimate 0.333
- REVEL 0.13
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available