A23T (p.Ala23Thr) variant of ANGPTL4 (Angiopoietin-related protein 4)
A23T (p.Ala23Thr) in ANGPTL4 (Angiopoietin-related protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A23T (p.Ala23Thr) variant details
- p.Ala23Thr
- cosmic curated COSV10003
- ExAC rs753864074
- TOPMed rs753864074
- gnomAD rs753864074
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.14
- CADD 24.30
- PolyPhen-2 0.55
- SIFT 0.01
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available