T64K (p.Thr64Lys) variant of ANGPTL3 (Angiopoietin-related protein 3)
T64K (p.Thr64Lys) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
T64K (p.Thr64Lys) variant details
- p.Thr64Lys
- ExAC rs756641927
- TOPMed rs756641927
- gnomAD rs756641927
- Missense
- Variant Prioritization Score for Impact Estimate 0.552
- REVEL 0.47
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available