S81Y (p.Ser81Tyr) variant of ANGPTL3 (Angiopoietin-related protein 3)
S81Y (p.Ser81Tyr) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
S81Y (p.Ser81Tyr) variant details
- p.Ser81Tyr
- gnomAD 1-62597808-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.447
- REVEL 0.38
- CADD 23.70
- PolyPhen-2 0.98
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available