S16P (p.Ser16Pro) variant of ANGPTL3 (Angiopoietin-related protein 3)
S16P (p.Ser16Pro) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
S16P (p.Ser16Pro) variant details
- p.Ser16Pro
- gnomAD 1-62597612-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- REVEL 0.05
- CADD 19.40
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available