R36S (p.Arg36Ser) variant of ANGPTL3 (Angiopoietin-related protein 3)
R36S (p.Arg36Ser) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
R36S (p.Arg36Ser) variant details
- p.Arg36Ser
- TOPMed rs1319925385
- gnomAD rs1319925385
- Missense
- Variant Prioritization Score for Impact Estimate 0.455
- REVEL 0.46
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available