Q21R (p.Gln21Arg) variant of ANGPTL3 (Angiopoietin-related protein 3)
Q21R (p.Gln21Arg) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
Q21R (p.Gln21Arg) variant details
- p.Gln21Arg
- gnomAD 1-62597628-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.06
- CADD 12.10
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available