Q21K (p.Gln21Lys) variant of ANGPTL3 (Angiopoietin-related protein 3)
Q21K (p.Gln21Lys) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
Q21K (p.Gln21Lys) variant details
- p.Gln21Lys
- gnomAD 1-62597627-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.14
- CADD 10.30
- PolyPhen-2 0.00
- SIFT 0.76
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available