P33L (p.Pro33Leu) variant of ANGPTL3 (Angiopoietin-related protein 3)
P33L (p.Pro33Leu) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
P33L (p.Pro33Leu) variant details
- p.Pro33Leu
- gnomAD 1-62597664-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.17
- CADD 23.00
- PolyPhen-2 0.14
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available