M39T (p.Met39Thr) variant of ANGPTL3 (Angiopoietin-related protein 3)
M39T (p.Met39Thr) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
M39T (p.Met39Thr) variant details
- p.Met39Thr
- TOPMed rs1336207471
- gnomAD rs1336207471
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.25
- CADD 23.90
- PolyPhen-2 0.77
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available