L6P (p.Leu6Pro) variant of ANGPTL3 (Angiopoietin-related protein 3)
L6P (p.Leu6Pro) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
L6P (p.Leu6Pro) variant details
- p.Leu6Pro
- ExAC rs766251086
- gnomAD rs766251086
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.15
- CADD 23.00
- PolyPhen-2 0.03
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available