L6F (p.Leu6Phe) variant of ANGPTL3 (Angiopoietin-related protein 3)
L6F (p.Leu6Phe) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
L6F (p.Leu6Phe) variant details
- p.Leu6Phe
- gnomAD 1-62597582-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0762
- REVEL 0.07
- CADD 3.65
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available