K63M (p.Lys63Met) variant of ANGPTL3 (Angiopoietin-related protein 3)
K63M (p.Lys63Met) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
K63M (p.Lys63Met) variant details
- p.Lys63Met
- ESP rs146749211
- ExAC rs146749211
- TOPMed rs146749211
- gnomAD rs146749211
- Missense
- Variant Prioritization Score for Impact Estimate 0.677
- REVEL 0.70
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available