K63E (p.Lys63Glu) variant of ANGPTL3 (Angiopoietin-related protein 3)
K63E (p.Lys63Glu) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
K63E (p.Lys63Glu) variant details
- p.Lys63Glu
- TOPMed rs1649482350
- gnomAD rs1649482350
- Missense
- Variant Prioritization Score for Impact Estimate 0.595
- REVEL 0.57
- CADD 26.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available