I77M (p.Ile77Met) variant of ANGPTL3 (Angiopoietin-related protein 3)
I77M (p.Ile77Met) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
I77M (p.Ile77Met) variant details
- p.Ile77Met
- gnomAD rs1156523401
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.23
- CADD 23.30
- PolyPhen-2 0.91
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available