I10T (p.Ile10Thr) variant of ANGPTL3 (Angiopoietin-related protein 3)
I10T (p.Ile10Thr) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
I10T (p.Ile10Thr) variant details
- p.Ile10Thr
- gnomAD rs1447204425
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.26
- CADD 18.20
- PolyPhen-2 0.21
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available