H62P (p.His62Pro) variant of ANGPTL3 (Angiopoietin-related protein 3)
H62P (p.His62Pro) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
H62P (p.His62Pro) variant details
- p.His62Pro
- TOPMed rs1356877257
- gnomAD rs1356877257
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.32
- CADD 25.20
- PolyPhen-2 0.96
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available