G66D (p.Gly66Asp) variant of ANGPTL3 (Angiopoietin-related protein 3)
G66D (p.Gly66Asp) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
G66D (p.Gly66Asp) variant details
- p.Gly66Asp
- ExAC rs755058329
- TOPMed rs755058329
- gnomAD rs755058329
- Missense
- Variant Prioritization Score for Impact Estimate 0.505
- REVEL 0.31
- CADD 24.70
- PolyPhen-2 0.87
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available