F72L (p.Phe72Leu) variant of ANGPTL3 (Angiopoietin-related protein 3)
F72L (p.Phe72Leu) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
F72L (p.Phe72Leu) variant details
- p.Phe72Leu
- ExAC rs775299081
- TOPMed rs775299081
- gnomAD rs775299081
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.13
- CADD 22.80
- PolyPhen-2 0.32
- SIFT 0.10
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available