F37S (p.Phe37Ser) variant of ANGPTL3 (Angiopoietin-related protein 3)
F37S (p.Phe37Ser) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
F37S (p.Phe37Ser) variant details
- p.Phe37Ser
- gnomAD 1-62597676-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.622
- REVEL 0.59
- CADD 28.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available