F37L (p.Phe37Leu) variant of ANGPTL3 (Angiopoietin-related protein 3)
F37L (p.Phe37Leu) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
F37L (p.Phe37Leu) variant details
- p.Phe37Leu
- gnomAD rs1326631750
- Missense
- Variant Prioritization Score for Impact Estimate 0.548
- REVEL 0.47
- CADD 27.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available