F2I (p.Phe2Ile) variant of ANGPTL3 (Angiopoietin-related protein 3)
F2I (p.Phe2Ile) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
F2I (p.Phe2Ile) variant details
- p.Phe2Ile
- ExAC rs772988115
- gnomAD rs772988115
- Missense
- Variant Prioritization Score for Impact Estimate 0.0865
- REVEL 0.04
- CADD 11.40
- PolyPhen-2 0.01
- SIFT 0.29
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available