F26L (p.Phe26Leu) variant of ANGPTL3 (Angiopoietin-related protein 3)
F26L (p.Phe26Leu) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
F26L (p.Phe26Leu) variant details
- p.Phe26Leu
- ESP rs143189908
- ExAC rs143189908
- TOPMed rs143189908
- gnomAD rs143189908
- Missense
- Variant Prioritization Score for Impact Estimate 0.0817
- REVEL 0.04
- CADD 9.14
- PolyPhen-2 0.00
- SIFT 0.54
- Most common in the HGDP:BANTUSOUTHAFRICA population (allele frequency 0.062)
- Structural context available