D79Y (p.Asp79Tyr) variant of ANGPTL3 (Angiopoietin-related protein 3)
D79Y (p.Asp79Tyr) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
D79Y (p.Asp79Tyr) variant details
- p.Asp79Tyr
- ExAC rs767345973
- TOPMed rs767345973
- gnomAD rs767345973
- Missense
- Variant Prioritization Score for Impact Estimate 0.67
- REVEL 0.58
- CADD 26.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available