D20Y (p.Asp20Tyr) variant of ANGPTL3 (Angiopoietin-related protein 3)
D20Y (p.Asp20Tyr) in ANGPTL3 (Angiopoietin-related protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
D20Y (p.Asp20Tyr) variant details
- p.Asp20Tyr
- Ensembl rs1557775786
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.18
- CADD 23.30
- PolyPhen-2 0.53
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available